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[6] [7] This brief duration has led to the development of GLP-1 receptor agonists (such as semaglutide and liraglutide), which are DPP-4-resistant analogues with prolonged half-lives, and DPP-4 inhibitors as therapeutic agents for type 2 diabetes

They are safe dietary supplements compliant with current regulations

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Selenium (Na(2)SeO(3)) upregulates expression of immune genes and blood-testis barrier constituent proteins of bovine Sertoli cell in vitro

Both have generally well-tolerated safety profiles in healthy patients without contraindications

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