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B2261, Sigma-Aldrich, Saint Louis, MO, USA) for 5 min at room temperature
The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development
These include early pharmacokinetic limitations, inadequate receptor selectivity, poorly chosen clinical endpoints, or the absence of enabling technologies at the time of initial evaluation
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