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There is no placebo group

But even splits are not the only option

Aversion to fatty or rich foods is another observation

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Feasibility and safety of intranasally administered mesenchymal stromal cells after perinatal arterial ischaemic stroke in the Netherlands (passion): a first-in-human, open-label intervention study

If one injection absorbs 28% less efficiently because you used a thigh site instead of the abdomen, the relative activation of GLP-1, GIP, and glucagon receptors might shift slightly