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[4] The proposed mechanism of action, based only on preclinical animal studies, involves potential modulation of growth factor pathways, particularly vascular endothelial growth factor (VEGF), which may promote angiogenesisthe formation of new blood vessels

doi:10.1001/jamainternmed.2018.4673 14.Mercadante S, Villari P, Ferrera P, David F, Intravaia G

IL-10 Suppresses Th17 Cells and Promotes Regulatory T Cells in the CD4+ T Cell Population of Rheumatoid Arthritis Patients

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Zhao LH, Yuan QN, Dai AT, He XH, Chen CW, Zhang C, et al