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In contrast, L-carnitine has been shown to activate mTOR signaling in the skeletal muscle of rats ( via the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway (Supplementary Figure S1), suggesting that L-carnitine directly affects the mTOR pathway

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Combined exercise and GLP-1 therapy maintained 5.1 kg greater weight reduction versus GLP-1 alone at one year post-treatment in research trials

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