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A standard weight loss workup at our clinic includes: Fasting insulin and HOMA-IR, a direct measure of insulin resistance Hemoglobin A1C A full thyroid panel, including Free T3, Free T4, and Reverse T3 (not just TSH) Comprehensive sex hormone panels for both men and women Cortisol patterns Inflammatory markers Advanced lipid particle analysis A DEXA body composition scan to precisely measure fat mass, lean mass, visceral fat, and bone mineral density That diagnostic picture determines the protocol

Blood pressure: GHK can lower blood pressure at high doses

The Frequency for B12 shots is every ten days

Step down one dose level at a time rather than stopping abruptly

Tilley MR, Cagniard B, Zhuang X, Han DD, Tiao N, Gu HH

If symptoms persist beyond dose escalation, clinical review is needed to distinguish between medication effects and a separate functional bowel disorder