Diabetes Care 29:2638-2643, 2006
The EVOKE and EVOKE + trials are supported by robust preclinical evidence demonstrating GLP-1RA benefits in neurodegeneration and cognitive enhancement in T2DM patients (Norgaard et al., 2022)
Liraglutide (Victoza, Saxenda): The SmPC similarly specifies refrigerated storage at 2C to 8C before first use, with in-use stability guidance
Enhanced metabolism Semaglutides effect on metabolism is another reason why some individuals experience increased energy levels
Additionally, it improves liver enzyme levels, reduces steatosis and stiffness, and thereby reduces the risk of liver fibrosis
Your doctor may be able to reduce the intensity of side effects by beginning on a lower dose and then slowly increasing it