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Based on published clinical data for semaglutide and tirzepatide the general progression looks like this: Weeks 1 to 4: Appetite reduction and faster feelings of fullness are usually the first changes noticed
I just think that is always in my mind of like, Is this safe for someone to do, and is this going to have any long-term effects? To Lennys point, theres one study in PFJ, like 7 of 12 patients reported subjective improvement in 6 months
Cell Death & Disease, 12 (9), 796
Nemeth C, Humpeler S, Kallay E, Mesteri I, Svoboda M, Rgelsperger O, Ekmekcioglu C (2011) Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas
Available from: Schwartz J, Chaudhry UI, Suzo A, et al
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