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B12 Deficiency and MTHFR: Individuals with MTHFR mutations may also be more prone to Vitamin B12 deficiencies

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doi: 10.3389/fphar.2025.1602976 Received 30 March 2025 Revised 13 November 2025 Accepted 14 November 2025 Published 19 December 2025 Volume 16 - 2025 Edited by Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by Kacper Nijakowski, Poznan University of Medical Sciences, Poland Miriam Njoki Karinja, Science for Africa Foundation, Kenya Updates Copyright 2025 Mazur, Ndokaj, Salerno, Vallone, Ardan, Bietolini, Carrouel, Wilk, Sarig, Ottolenghi and Bourgeois

If you'll be giving yourself shots at home (after proper training from us, of course!), always use a new needle and syringe each time and dispose of them safely in a special sharps container

It seems timely to think again about why this was needed, what it says and when and how it applies

This is actually the sweet spot for 10mg vials