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it depletes GSH indirectly through oxidation, and enzyme activity may decline secondarily (~35% in some studies), but this is not the primary cause. Option (D): Primaquine decreases reduced glutathione levels by promoting its oxidation to combat ROS, not increases them. Introduction: Unraveling Primaquine Hemolytic Anemia and NADPH Demand Primaquine hemolytic anemia strikes G6PD-deficient patients when the drugs metabolites spike NADPH demand for antioxidant protection

Attend follow-up sessions if recommended

The highest caspase immunoexpressing score was given to the Dexa group, and the score of the spirulina group was significantly lower (Figure 6)

One such alternative would be a sulforaphane (10) supplement

SUMOylation refers to a post-translational modification in which small ubiquitin-like modifier (SUMO) proteins are attached to specific sites of a target protein, altering its conformation and activity without inducing degradation [103]