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Toxicol Lett 70(2):243251
A 2025 perspective proposed that GLP-1s could influence epigenetic pathways involved in fibrosis and hepatocellular carcinoma risk in the aging liver [6]
Individual results may vary based on numerous factors including genetics, adherence, lifestyle, and concurrent health conditions.
Clinical trials have shown their efficacy and safety over several years, yet the possibility of long-term adverse effects remains a research focus
Future research studies should prioritize large multicenter RCTs that apply standardized diagnostic criteria and validated depression rating scales
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
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