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PT-141 should not be used by patients with uncontrolled hypertension or known cardiovascular disease

This protocol is not appropriate for everyone

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This injectable medication, containing the same active ingredient as Ozempic, is specifically approved for chronic weight management

With that proof of concept in hand, we then investigated the possibility of combining the peptide/oligourea hybrid approach with the protraction strategy, which consists of functionalizing a peptide with a fatty acid chain to promote its binding to albumin and prolong its in vivo half-life

doi: 10.3390/jcm9082586 6 BruneK.RennerB.TiegsG