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Before entering the dormant stage, Mtb starts to accumulate the lipids derived from the host cell membrane degradation and later hydrolyze them to reactivate the infection process

However, inhibition of DPP-4 also potentiates the stem cell chemokine, stromal cell-derived factor-1 (SDF-1), which can promote inflammation, proliferative responses and neovascularization

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Dependent on both innate and adaptive immunity, immunohealth can be affected by many lifestyle factors from exercise and sleeping habits to diet and stress management

Abbass NJ, Nahlawi R, Shaia JK, et al

7 Moreover, obesity prevalence, a key risk factor for DM, has seen a substantial rise globally and in Saudi Arabia