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Contreras-Verduzco 2 , Nieto-Martnez Sandra 3 , David Monterrosas-Ustarn 4 1 Primary Immunodeficiencies Laboratory, Instituto Nacional de Pediatra, Mexico City, Mexico
Semaglutide and tirzepatide are GLP-1 receptor agonists (tirzepatide also targeting GIP), mimicking gut hormones that regulate satiety and blood sugar a well-established pathway with extensive human data
Insulin secretion in response to GLP-1 occurs primarily under conditions of elevated plasma glucose, which explains the low risk of hypoglycemia associated with GLP-1based therapies
Ozempic and Wegovy are semaglutides, which help the pancreas release the right amount of insulin when blood sugar levels are high
The combination of significant weight reduction and effective glycemic control across diverse patient populations makes GLP-1 receptor agonists highly attractive, fueling their adoption worldwide and establishing them as a cornerstone in obesity and diabetes management
Your provider should check on your progress regularly
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