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Retatrutide (12 mg) is an investigational, long-acting synthetic peptide originally developed by Eli Lilly and evaluated in Phase 2 and ongoing Phase 3 clinical research
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The complete week-by-week retatrutide timeline The following timeline draws from phase 2 trial data involving 338 adults published in the New England Journal of Medicine, phase 3 data from Eli Lilly announcements, and the published qualitative study on participant experiences during the clinical trial
Standard research models include cultured pituitary cells, primary somatotrope preparations, and in-vivo rodent models with serum hormone measurement endpoints
They do not quantify how many patients might experience stomach paralysis or how impactful it can be on a persons daily life
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