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Mitochondria are also responsible for maintaining redox balancemanaging the natural by-products of metabolism known as reactive oxygen species (ROS)

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GIP (glucose-dependent insulinotropic polypeptide) receptor activation primarily enhances insulin secretion, improves fat tissue metabolism, and may contribute to central appetite suppression

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In parallel, the landscape of pharmacological therapies for T2DM and (to a lesser extent) obesity has expanded in recent decades with new classes of molecules coming into the market