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The research team identified that erastin could directly bind to VDAC2/3, leading to loss of mitochondrial function as well as the emission of substantial amounts of oxides, finally causing ferroptosis (Yagoda et al., 2007)
(2020) publicaron un metaanlisis en Nutrients con 14 ensayos clnicos aleatorizados (n=1,663) demostrando que el ALCAR reduce significativamente el dolor neuroptico (DM -0.82 en escala 010, p 50 aos) y buscas soporte tanto metablico como neuroprotector, o si padeces neuropata perifrica donde la evidencia clnica del ALCAR es consistente
Wang W-Y, Liu X, Gao X-Q, Li X, Fang Z-Z
Effect of L-carnitine supplementation on muscle cramps in liver cirrhosis: results from a retrospective cohort study
D.FinemanM
Disposition and metabolite kinetics of oral L-carnitine in humans
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