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mTOR: from growth signal integration to cancer, diabetes and ageing

41 Slc3a2-dependent BCAA metabolism also has a key role in the physiological activities of Foxp3 + Treg cells, and either BCAA deprivation or SLC3A2 mutation can induce impaired activation of the mTORC1 pathway in Treg cells and inhibit the immunosuppressive function of Treg cells

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For some individuals, particularly those with sensitive airways, inhaling glutathione may trigger wheezing or shortness of breath

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