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The glutathione pathway mediates high capacity NADPH-dependent antioxidative electron flux Having established the functionality of NAPstars in yeast, mammalian cells and plants, we next sought to address a longstanding question in redox biology, namely, the role of glutathione in cellular antioxidative responses
Ischemia reperfusion (I/R) injury model: reducing ischemic injury and restoring barrier function Intestinal ischemia-reperfusion injury is common in clinical scenarios such as shock and surgery, which can lead to epithelial cell necrosis and barrier damage
Gaullier JM et al
Key signalling proteins in infection and immunity that can be regulated by glutathionylation include p50 9 , STAT3 10 and HIV protease 11
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These enzymes require vitamin C to function
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