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Considering the paramount importance of oxLDL in the pathogenesis of atherosclerosis, it is reasonable to evaluate the role of antioxidants in the treatment of the disease as adjuvant strategies to lipid-lowering or anti-inflammatory therapies designed to reduce the risk of cardiovascular disease (230)

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Cardiovascular protection: the SELECT trial The SELECT trial was a landmark cardiovascular outcome study that enrolled 17,604 adults with established cardiovascular disease and overweight or obesity but without diabetes

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