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they can cross the blood-brain barrier to target neuronal mitochondria, and when loaded with curcumin, reduce mitochondrial oxidative stress and inhibit neuronal death (151)
The phosphorylated Gab1 creates additional binding sites for most downstream signaling molecules, which activate the different signaling pathways, including JAK/STAT3, phosphoinositide 3-kinase (PI3K)/Akt/NF-B, Ras/Raf, and mitogen-activated protein kinase (MAPK) cascades
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The effects of probiotics, prebiotics and synbiotics on the reduction of IBD complications, a periodic review during 20092020
Fisher WE, Boros LG, Schirmer WJ
Neuropathology 2014;34:284-90
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