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Reconstitution volumes and diluent choice for investigational peptides are specified in the trial protocol and IMPD they are not appropriate for individual self-use

Methionine and choline are generally more stable but can still be affected by prolonged heat exposure

Freezing is appropriate only for lyophilised powder before reconstitution (store at 20C)

This may indicate that the peptide has degraded or that the solution is contaminated

Patients with gastrointestinal disorders, such as Crohns disease, celiac disease, or those who have undergone gastrointestinal surgeries like bariatric surgery, may also find B12 injections advantageous

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