It has been reported that oral administration of D-allulose can stimulate GLP-1 secretion and thus be used to prevent and treat glucose intolerance ( Other Physiological Functions of D-Allulose D-Allulose exhibits anti-inflammatory effects by suppressing serum levels of proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-), interleukin 6 (IL-6), and monocyte chemoattractant protein 1 (MCP-1)
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Studies typically show improvements in fasting glucose, HbA1c, and HOMA-IR (a measure of insulin resistance) after 12-24 weeks of treatment
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