The 12 mg group saw a 4.5-point drop on the WOMAC pain scale (a 75.8% reduction), and roughly 1 in 8 participants on retatrutide became completely free of knee pain, compared with 1 in 24 on placebo
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Xing C, Zhao H, Zhang J, He B
The commercial incentive to be first is large enough to justify $550 million in ANDA preparation, bioequivalence studies, and patent litigation costs, sometimes multiples of that for complex molecules