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FIGURE 1: The crowded pipeline for weight management and obesity-related comorbidities By focusing so heavily on weight management and obesity-related endpoints, manufacturers risk repeating the mistake of late entrants to the statins market of the 1990s and 2000s, when products with weaker benefit failed to gain traction

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These two pathways work together to reduce appetite, slow gastric emptying, and improve how the body handles glucose and insulin

Research shows that training volume can be reduced by up to 66% without muscle loss as long as intensity remains high