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Because MCAS is multifactorial and highly individualized, care plans are typically layered and strategic rather than single-drug solutions

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DOI:10.1016/j.ad.2011.08.002

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Myeloid Deletion of SIRT1 Suppresses Collagen-Induced Arthritis in Mice by Modulating Dendritic Cell Maturation

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At baseline, the mean AHI was 51.5 in trial 1 and 49.5 in trial 2

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This makes it hard to draw firm conclusions about knee outcomes such as pain, function, or return to activity

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