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Carnitine deficiency occurs in various disorders, such as malnutrition, liver cirrhosis, endocrine disorders and end-stage renal disease treated with hemodialysis, all of which are considered to affect health-related quality of life (31,32)

If true, this would not favor long-term L-carnitine supplementation, or may require the development of additional strategies to reduce TMA/TMAO levels (56)

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This timing helps establish consistent eating patterns that complement medication schedules