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L-carnitine is one of these supplements and plays a pivotal role in cellular energy metabolism, as it is essential for the transport of long-chain fatty acids (LCFA) from the cytosol into the mitochondrial matrix, where LCFA are oxidized (3)
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Broad, J., Gralczyk, A., Mannur, K., Dukes, G
The two human 3-hydroxysteroid dehydrogenases have been investigated in detail by Thomas and coworkers (e.g., Thomas et al., 2005), and their studies indicate that the 3-ketosteroid 5-AD formed by oxidation of dehydroepiandrosterone with NAD + as a coenzyme remains as an intermediate bound to the enzyme prior to its isomerization to 4-AD