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Clinical data shows that most participants in tirzepatide trials regained significant weight within one year of stopping treatment
Bibcode:1964Natur.203.1068H
Davis Research, LLC conducted the field work between January and July 2025
Regarding renal health, the medication itself is not nephrotoxic, but the side effects (vomiting, diarrhea) can lead to dehydration, which may injure the kidneys
In both studies no difference was seen in normal vs renally impaired subjects
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