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20 Primarily, NADPH provides reducing equivalents for fatty acid synthase (FASN), the main rate-limiting enzyme, to synthesize fatty acids with acetyl-CoA serving as a primer and malonyl-CoA as a two-carbon donor, 21,22 and provides the needed electrons for ironsulfur (Fe/S) protein assembly that participate in non-essential amino acid biosynthesis and lipoic acid synthesis, tRNA modification, DNA replication and repair, and telomere maintenance

doi:10.1161/01.cir.94.1.19 Weber C, Erl W, Weber K, Weber PC

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These measurements revealed that repeated assembly led to the formation of smaller vesicles, characterized by a narrower and more uniform particle size distribution

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