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Genetic variants in methionine synthase, methylenetetrahydrofolate reductase (MTHFR), and homocysteine metabolism pathways influence how efficiently your body processes B12, informing whether standard or optimized dosing may be more appropriate

Vitamin B12 injections are generally considered to be very effective and almost always totally risk-free

Dialysis may be necessary if you develop severe kidney problems

Consulting with your health care provider about the best dosage for your specific needs is recommended

They consider the patients health history, how severe the deficiency is, and any conditions that might affect how well the body absorbs B12

Because this is a water-soluble vitamin, its not going to linger in your body as long as a fat-soluble one might