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Transdermal delivery - moving an active compound through the skin into systemic circulation - is scientifically established for certain molecules

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Ozempic is FDA-approved for the following conditions: To improve blood sugar control in addition to diet and exercise in people with type 2 diabetes To lower the risk of cardiovascular events in adults with type 2 diabetes and cardiovascular disease To lower the risk of kidney failure, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease Wegovy is FDA-approved for the following conditions: To reduce the risk of major cardiovascular events in adults who are obese or overweight and have cardiovascular disease To promote weight loss in obese adults and children 12 years of age and over (oral Wegovy is approved only for adults) To promote weight loss in overweight adults who have at least one other weight-related medical condition To treat metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate-to-advanced fibrosis

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Purely cosmetic treatments are generally not covered by standard health insurance policies or government welfare schemes

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