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The Stanford PNAS study noted striking sex-specific differences in this regard, finding that male ME/CFS and Long COVID patients exhibited pronounced mitochondrial lipid oxidative damage mediated by a failure in Glutathione Peroxidase 4 pathways

(PubMed) American Academy of Pediatrics, Committee on Nutrition

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Its primary mechanism is serving as the rate-limiting precursor for glutathione , the bodys most abundant endogenous antioxidant