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Compared to L-arginine, an advantage to supplementation with L-citrulline is that intestinal catabolism of L-citrulline is limited since it is not metabolized by arginases, and the activity of arginosuccinate synthase is low in enterocytes [2]

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Amino acids license kinase mTORC1 activity and T reg cell function via small G proteins Rag and Rheb

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