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This makes it difficult to isolate the independent contribution of GLP-1 medications
Furthermore, the secular trends of causes of mortality in patients with diabetes shows an increase for neurodegenerative causes (e.g., dementia) and liver diseases [65]
doi: 10.1016/0092-8674(95)90085-3 24 BylundJCampsallPAMaRCConwayBASpeertDP
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Small-scale clinical trials revealed that GLP-1 and GLP-1-based medicines may have positive effects on low-grade inflammation, blood pressure, cholesterol, and microcirculation ( Due to their various modes of action, which include vasodilation, natriuresis, glucose and weight control, and direct cardioprotective effects, GLP-1 receptor agonists have therapeutic potential for treatment of heart failure ( Obesity is a major cause of cardiovascular diseases
E.GosselinD.Lagier-TourenneC.ZuccatoC.et al (2014)
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