Importantly, not all obesity treatments work for all patients
"I tried everything," Lizzo told host Trisha Paytas during a June 2025 episode of the Just Trish podcast, before explaining why she wound up ditching GLP-1 medications early on in her journey
Despite the successes of GLP-1RAs, approximately half of patients who initiate them discontinue within the first year 8 , likely due to their considerable gastrointestinal side effects as well as limited access under insurance coverage policies and national prescribing guidelines
Women should evaluate whether menstrual cycle phase, perimenopause, or hormonal contraceptive use is creating a metabolic headwind
The most common are mild digestive issues such as nausea, dizziness, or bloating
Patients can only pay with credit or debit cards