They want improvement without surgery
DPPOS 10-year follow-up
Its defining feature is selectivity: unlike earlier GHRPs such as GHRP-2 and GHRP-6, ipamorelin produces minimal effect on cortisol, prolactin, or aldosterone secretion at typical research doses
Science 279 , 17181721 (1998)
However, in line with the specificity of CPA, the C-terminal residues of the L585I, L585M, and L585V variants were cleaved in vitro upon exposure to the enzyme for 5 hours at 37 C, as confirmed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis of the C-terminal peptides (Supplementary Table 1)
However, consistent dosage over the years may result in considerable cumulative effects