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mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion

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This process stabilizes the expression of the key transcription factor Foxp3, thereby promoting the differentiation of Tregs and enhancing their immunosuppressive functions (Hu M

Side effects are usually mild and temporary some patients feel slight nausea, dizziness or a headache during an IV drip, or minor tenderness at the injection site

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