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The SP@M recovers the balance of synovial microenvironment, and finally achieves bone remodeling and cartilage restoration in collagen-induced arthritis (CIA) mouse models (Fig

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The treatment also caused increased levels of oxidative stress markers in the liver, kidney, and brain tissues, including MDA, NO, SOD, catalase, glutathione, and GPx, revealing C-PC may aid in reducing inflammation, and affects oxidative stress pathways

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