However, slowing the digestive process can disrupt the normal movement of stool through your intestines, leading to either constipation or loose stools depending on your individual gut biology
M., Sanna, E., Deiana, L., Panzone, F., Contu, P., and Floris, C
In fact, these same medications are now being investigated for some serious and potentially permanent side effects, including vision loss
Balancing Weight and Muscle Loss in GLP1 Receptor Agonist Therapy. Nature Reviews Endocrinology , 28 July 2025
Tirzepatide activates GLP-1 receptors in skeletal muscle tissue
Orforglipron (Foundayo) is a daily tablet that works on the GLP-1 pathway to reduce appetite, while Mounjaro is a weekly injection that targets both GLP-1 and GIP, making it more potent