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They are generating mice in which the protein SPHKAP can be specifically deleted from -cells, allowing them to examine how disrupting this signalling hub affects pancreatic function and GLP-1R signalling
Particles can indicate denatured protein precipitating out of solution, contamination, or crystallization
At ~3.33 mg/mL, 1 unit 33 mcg total
And we still don't really know why the AI is so good, but it just, that is perhaps the best single example of the gap between human eye discrimination and what an AI, when it's seen, trained with hundreds of thousands of images, it just, it's actually pretty mind boggling to me
Will the superior efficacy outweigh the tolerability concerns
It's also a period when the body adapts more fully to Ozempic, potentially leading to more significant weight loss
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