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doi: 10.1111/dom.12825 32 PittampalliSUpadyayulaSMekalaHMLippmannS

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That demonstration typically requires a substantial analytical comparability package, often including pharmacokinetic and pharmacodynamic bridging studies, and in some cases, comparative efficacy or safety clinical trials

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GLP-1 agonists have shown direct benefits in slowing the progression of kidney disease , independent of their effects on blood sugar or weight [8, 9]

PubMed Greendale GA, Sternfeld B, Huang M, et al