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Grx exhibit site-specific distribution with Grx1 being specifically located in cytosol while Grx2 localizes in mitochondria
This creates a therapeutic opportunity, as the same oxidative stress can be leveraged to trigger cell death in malignant cells (125)
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Psoriasis symptoms are exacerbated by a variety of external pro-oxidative stress factors, including narcotics, smoking, drinking alcohol, stress, and bacterial infections [36, 37]
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