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There is research suggesting that methylcobalamin may be particularly supportive in neurological conditions compared to cyanocobalamin, likely because of its direct involvement in methylation and nerve tissue repair

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Geneva: International Organization for Standardization, 2016

Amount of vitamin b12 that reaches blood: Vitamin B12 Injection For Dogs Delivers Larger Amount Of Cobalamin In Blood-Picture Courtesy: MetLife Pet Insurance By giving vitamin b12 orally, you cannot estimate what amount of nutrient that has reached the blood

arXiv preprint arXiv:2502.14239

Specifically, the National Health and Nutrition Examination Survey estimated that 3.2% of adults over age 50 have seriously low levels of B12, and up to 20% may have a borderline deficiency