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Although lecithin, creatinine and betaine are technically precursors to TMA, pilot studies have shown no significant effect on the production of excess TMA/TMAO in urinary analysis at normal dietary levels of consumption

Protein S-nitrosylation involves the attachment of NO to the reactive thiol group of a cysteine in a target protein generating an S-nitrosothiol (SNO)

In early chronic kidney disease, dietary strategies can help cats maintain body weight and lean muscle mass (Hall JA, 2019)

Untreated late disseminated Lyme disease may also result in joint or tissue damage

It is also possible that selenium may have beneficial effects in moderate-to-severe GO, especially when patients are selenium-deficient

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