2 Literature search strategy Recent literature of this narrative review was identified through searches of Web of Science Core Collection, PubMed, Science Direct, and Google Scholar using combinations of keywords related to flavonoid biosynthesis, phenylpropanoid pathway, structure-activity relationships, biotic stress, abiotic stress, combined stress, secondary metabolism, redox homeostasis, phytohormone signaling, metabolic flux, metabolic branch points, pathway competition, metabolic trade-off, multi-omics, artificial intelligence, machine learning, CRISPR/Cas systems, and metabolic engineering
For T0901317 experiments, mice were injected intraperitoneally with either vehicle (10%DMSO in 90% corn oil) or T0901317 (MedChem Express, HY-10626) at a dose of either 16.9 mg/kg or 50 mg/kg dose for either 4 days (1720) days post AAV-TBG-Cre treatment) or 14 days (720) days post AAV-TBG-Cre treatment)
Despite interest in human clinical trials, BPC-157 hasnt yet reached this stage
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