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Participants were an average age of 72 years
Pre-treatment of HUVECs with metformin (0.1, 0.5 and 1.0 mmol/L) or liraglutide (3, 10, 30 and 100 nmol/L) was performed 2 h prior to the PA exposure and in 22 h duration
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The study also examined the percentage of time spent in off periods, which are times when medication effectiveness decreases and PD symptoms worsen
It supports studies of tissue response signaling, cell behavior, and cytoskeleton associated pathways in controlled in vitro and preclinical model systems
The postoperative recovery went smoothly, and the surgical wounds healed well
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