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Reconstitution: Choose the solvent appropriate to the experimental use: HPLC-grade or equivalent purified water for analytical work, sterile low-endotoxin or cell-culture-grade solvent for cell-based assays, and a validated buffer system for biological activity experiments

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Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis