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Increases endogenous IGF-1, promotes thermogenesis, and supports lean muscle mass development
Many new questions about the mechanism of DNA methylation-mediated gene expression regulation in mammals have appeared: (i) what is the role of non-CG methylation in stem cells, in which it appears enriched on transcribed strands of gene bodies of highly active genes (Lister et al., 2009), and does it occur in different cell types as suggested in some studies
Each of these options has its own mechanism, evidence base, and risk profile
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doi:10.3390/ctn7020013 81
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