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Clinical features Increased RBCs lead to an increase in blood viscosity that is associated with Abnormal cerebral blood flow leading to headache Abnormal Retinal flow Visual disturbance Increased risk of thromboembolic events stroke gangrene myocardial infarction pulmonary embolism deep vein thrombosis Microvessel thrombosis (episodic blood clots) leads to Erythromelalgia (hyperemic and painful extremities) Dysfunctional platelets Increased risk of thromboembolic events and bleeding Increased number of RBCs Increased splenic destruction of RBCs leading to Splenomegaly Increased RBC destruction increased uric acid and LDH release due to cell lysis increased uric acid levels cause the formation of uric acid crystals in Joints Gout

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Mounjaro's Approved Uses in the UK In the United Kingdom, Mounjaro has received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) for two primary indications

Wegovy Lawsuits Most people don't realize that the same drug, with two brand names and two FDA approvals, is at the center of this litigation

Review Authenticity Good Mixed across multiple platforms Trustpilot & Google Reviews Good 4.2/5 across 625+ reviews Reddit & Community Sentiment Good Positive on pricing, mixed on pharmacy switching

For patients with no pre-existing SUD, GLP-1 use was associated with a 14% lower overall risk of developing any new substance use disorder